03/05/2008
12:00 - 20:00		Registration
17:30 - 19:30		Opening Ceremony: Geoffrey Harris Prize Lecture HALL 1 Chair: E. Nieschlag (Germany), President ESE
	GH1	From Geoffrey Harris' hypothalamic principle to a unified theory of stress and stress system disorders G. Chrousos (Greece)
17:30 - 19:30		Opening Ceremony: European Journal of Endocrinology Prize Lecture HALL 1 Chair: C. Strasburger (Germany), Editor EJE
	EJE1	Sex Steroids in the Regulation of Bone Metabolism in Men C. Ohlsson (Sweden)
19:30 - 22:00		Welcome Reception EXHIBITION
04/05/2008
08:30 - 10:00		Symposium 1 - Clinical: The trick is the combination HALL 1 Chairs: A. van der Lely (Netherlands) & V. Pirags (Lithuania)
08:30	S1.1	Treatment of hyperthyroidism: block and replace versus titration L. Bartalena (Italy)
08:50	S1.2	The combination of GH/IGF-I makes the difference! J. Janssen (Netherlands)
09:10	S1.3	Medical Treatment of Acromegaly: Dual Blockade with a Somatostatin Analog and Pegvisomant J. O. Jorgensen (Denmark)
09:30	S1.4	The combined Androgen and Estrogen replacement therapy in women W. Arlt (UK)
08:30 - 10:00		Symposium 2 - Basic: The TGF-beta Superfamily HALL 7 Chairs: C.V. Alvarez (Spain) & D. Salvatore (Italy)
08:30	S2.1	BMP to the Bone P. ten Dijke (Netherlands)
08:50	S2.2	Integration of Skeletal Regulatory Signals in Nuclear Microenvironments G. Stein (USA)
09:10	S2.3	TGF-beta family ligands in glucose and fat homeostasis in adults A. Schneyer (USA)
09:30	S2.4	The Dependence Receptor notion: When apoptosis regulates tumor progression and metastasis P. Mehlen (France)
08:30 - 10:00		Symposium 3 - Translational: Gene / Environment interactions in autoimmune endocrine disease HALL 3 Chairs: M. Knip (Finland) & G. Krassas (Greece)
08:30	S3.1	Why is the incidence of autoimmune diseases increasing in the modern world? J. F. Bach (France)
08:50	S3.2	Genome-wide association studies and hormone-dependent cancers D. Hunter (USA)
09:10	S3.3	Gene Environment Interactions in Type 1 Diabetes G.S. Eisenbarth (USA)
09:30	S3.4	Gene-environment interactions in thyroid autoimmunity. L. Hegedüs (Denmark)
10:05 - 10:50		Plenary Lecture 1 Supported by Bayer-Schering Pharma HALL 1 Chairs: S. Lamberts (Netherlands) & F. Casanueva (Spain)
10:05	PL1	Estrogens and cardiovascular disease M. E. Mendelssohn (USA)
10:50 - 11:15		Coffee Break & Exhibition
11:15 - 12:45		Symposium 4 - Clinical: Is there a crisis of male reproduction? HALL 1 Chairs: A. Milewicz (Poland) & M. Simoni (Italy)
11:15	S4.1	Deterioration of male reproductive function in Europe. Geographical differences N. Joergensen (Denmark)
11:35	S4.2	Life style factors and chemical exposures impair male reproductive development and function in humans K. Main (Denmark)
11:55	S4.3	Metabolic syndrome in Klinefelter syndrome (47,XXY) A. Bojesen (Denmark)
12:15	S4.4	Metabolic Aspects of Testosterone Replacement M. Zitzmann (Germany)
11:15 - 12:45		Symposium 5 - Basic: Protein modifications / Proteomics HALL 7 Chairs: S.B. Bravo (Spain) & A.Vidal (Spain)
11:15	S5.1	Comparative proteomics as a tool in biology: The protein microscope T. Nilsson (Sweden)
11:35	S5.2	Applying proteomics to thyroid tumour diagnosis D. Führer (Germany)
11:55	S5.3	Targeting ubiquitin networks I. Dikic (Germany)
12:15	S5.4	Progesterone Receptor Responses Modified by SUMO in the Endometrium J. J. Brosens (UK)
11:15 - 12:45		Symposium 6 - Translational: Insights in pancreatic development and new clinical aspects HALL 3 Chairs: K. Raile (Germany) & G. Bolli (Italy)
11:15	S6.1	Embryonic Pancreatic Development F. M. Spagnoli (USA)
11:35	S6.2	The zinc-finger factor Insm1 (IA-1) is essential for the development of endocrine cells of the pancreas, intestine and adrenal gland. C. Birchmeier (Germany)
11:55	S6.3	Hyperinsulinism in humans K. Hussain (UK)
12:15	S6.4	Carboxylester lipase (CEL) VNTR links exocrine dysfunction to endocrine dysfunction P. R. Njolstad (Norway)
11:15 - 12:45		Oral Communication 1: Neuroendocrinology & Pituitary HALL 4/5 Chairs: S. Tsagarakis (Greece) & A. Giustina (Italy)
11:15	OC1.1	Structured assessment of neuroendocrine dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage in 921 patients – the German Interdisciplinary Database Presenter: H. Schneider (Germany)
11:25	OC1.2	The adequacy of thyroxine replacement in hypopituitary patients Presenter: H. Filipsson (Sweden)
11:35	OC1.3	Limited effects of Growth Hormone Replacement in Adultswith Growth Hormone Deficiency after Treatment for Acromegaly Presenter: A. van der Klaauw (Netherlands)
11:45	OC1.4	Pasireotide (SOM230) effectively reduces pituitary tumor volume in patients with active acromegaly: preliminary 6-month results from a Phase II extension study Presenter: A. J. Farrall (UK)
11:55	OC1.5	CARDIAC PERFORMANCE AFTER LONG-TERM TREATMENT WITH PEGVISOMANT IN PATIENTS WITH ACROMEGALIC : A RADIONUCLIDE ANGIOGRAPHY STUDY. Presenter: R. S. Auriemma (Italy)
12:05	OC1.6	The metabolic effects of ghrelin and glucocorticoids are mediated by AMP-activated protein kinase (AMPK) and endogenous cannabinoids Presenter: B.Kola (UK)
12:15	OC1.7	INTERMITTENT HIGH GLUCOSE CONCENTRATIONS REDUCE NEURONAL PRECURSOR PROLIFERATION BY ALTERING THE IGF SYSTEM: THE INVOLVEMENT OF THE NEUROPROTECTIVE FACTOR SELADIN-1. Presenter: A. Peri (Italy)
12:25	OC1.8	Differential sensitivity of men and women to anorexigenic and memory improving effects of intranasal insulin Presenter: C.Benedict (Germany)
12:35	OC1.9	Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men Presenter: G Vila (Austria)
13:00 - 14:30		Satellite Symposium: Lilly - New treatment approaches for type 2 diabetes mellitus that target pathophysiology HALL 3
13:00 - 14:30		Satellite Symposium: Ipsen - Pathogenesis & management of aggressive pituitary tumours HALL 1
13:00 - 15:00		Lunch
13:00 - 15:00		Poster session
14:30 - 15:30		Meet the Expert 1: The impact of abdominal obesity HALL 1
14:30	ME1	The impact of abdominal obesity D. Micic (Serbia)
14:30 - 15:30		Meet the Expert 2: The necessity of Insulin analogues HALL 7
14:30	ME2	Rational for using insulin analogues in the treatment of diabetes mellitus G.B. Bolli (Italy)
14:30 - 15:30		Meet the Expert 3: Contraception in the new millennium HALL 3
14:30 - 15:30	ME3	Contraception in the New Millennium G. Mastorakos (Greece)
14:30 - 15:30		Meet the Expert 4: A living method: In vivo microscopy HALL 4/5
14:30	ME4	Two-photon microscopy of cancer invasion and metastasis P. Friedl (Germany)
15:30 - 17:00		Symposium 7 - Translational: The functions of peripheral GHrelin HALL 1 Chairs: C. Dieguez (Spain) & M. Korbonits (United Kingdom)
15:30	S7.1	Ghrelin and the Gonads M. Tena-Sempere (Spain)
15:50	S7.2	Ghrelin and the endocrine pancreas R. Granata (Italy)
16:10	S7.3	Ghrelin and Bone P.J. Delhanty (Netherlands)
16:30	S7.4	Peptidyl growth hormone secretagogues in cardioprotection H. Ong (Canada)
15:30 - 17:00		Symposium 8 - Basic: Nuclear Receptors HALL 7 Chairs: A. Aranda (Spain) & G. Vollmer (Germany)
15:30	S8.1	LXR E. Saez (USA)
15:50	S8.2	Kinase signaling and retinoic acid nuclear receptors C. Rochette-Egly (France)
16:10	S8.3	Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation R. Schüle (Germany)
16:30	S8.4	Estrogen-related receptors as regulators of energy homeostasis and adaptive metabolism A. Kralli (USA)
15:30 - 17:00		Symposium 9 - Clinical: New aspects of adrenal disease HALL 3 Chairs: B. Allolio (Germany) & J. Bertherat (France)
15:30	S9.1	The role of toll-like receptors K. Zacharowski (Germany)
15:50	S9.2	The expanding spectrum of DAX1 and SF1 mutations J. Achermann (UK)
16:10	S9.3	REPLACEMENT AND QoL IN PATIENTS WITH ADRENAL INSUFFICIENCY G. Johansson (Sweden)
16:30	S9.4	Genetics of chromaffin tumours A-P. Gimenez-Roqueplo (France)
15:30 - 17:00		Oral Communication 2: Thyroid HALL 4/5 Chairs: R. Elisei (Italy) & B. Jarzab (Poland)
15:30	OC2.1	Analysis of early gene expression in mouse thyroid development Presenter: C. Hübner (Germany)
15:40	OC2.2	Identification of 25 novel NKX2-1 gene mutations in 100 patients with broad spectrum of brain and thyroid dysfunctions Presenter: A. Thorwarth (Germany)
15:50	OC2.3	Global Proteomic analysis in human thyroid proliferative/neoplastic primary culture lines Presenter: S.B.Bravo (Spain)
16:00	OC2.4	Identification and enrichment of thyroid stem cells in anaplastic cell lines. Presenter: G. Zito (Italy)
16:10	OC2.5	Fetal cell microchimerism in papillary thyroid cancer: A possible role in tumor damage and tissue repair Presenter: V. Cirello (Italy)
16:20	OC2.6	Ga-68-Dotatoc PET detects Somatostatin receptors in normal thyroids and various thyroid pathologies Presenter: J. Singer (Germany)
16:30	OC2.7	Impact of Resistance to Thyroid Hormone on the Cardiovascular System in Adult Humans Presenter: M. Pulcrano (Italy)
16:40	OC2.8	Graves’ ophthalmopathy in patients treated with radioiodine I-131 Presenter: A. Baldys-Waligorska (Poland)
16:50	OC2.9	Subclinical hypothyroidism in older patients: an analysis of natural course and risk factors for the thyroid failure Presenter: A. H. Djezairi (Algeria)
17:15 - 18:00		Plenary Lecture 2 HALL 1 Chairs: I. Gerendai (Hungary) & J. Wass (United Kingdom)
17:15	PL2	Why did Moses live to be 120? N.Barzilai (Israel)
18:00 - 18:15		Coffee
18:15 - 19:45		Satellite Symposium: Novartis Oncology - Optimal management of acromegaly - today, tomorrow and throughout a patient's life HALL 3
18:15 - 19:45		Satellite Symposium: Pfizer - KIMS Highlights: Does GH replacement have an impact on mortality rate in adult hypopituitary patients? HALL 1
05/05/2008
08:30 - 10:00		Symposium 10 - Pro & Con: Is there a rationale for ISS treatment with GH HALL 1 Chair: P. Clayton (UK)
		CON M. O. Savage (UK)
		PRO J.M. Wit (Netherlands)
08:30 - 10:00		Symposium 11 - Basic: Epigenetics in endocrinology HALL 7 Chairs: H. Krude (Germany) & L. Hofland (Netherlands)
08:30	S11.1	Epimutations in the human genome B. Horsthemke (Germany)
08:50	S11.2	Mechanisms of selective gene expression in development V. van Heyningen (UK)
09:10	S11.3	Epigenetics in mammalian development M. Zernicka-Goetz (UK)
09:30	S11.4	Imprinting in Human Disease – Lessons from the study of Transient Neonatal Diabetes K. Temple (USA)
08:30 - 10:00		Symposium 12 - Translational: Addicted to Food? HALL 3 Chairs: S. Farooqi (UK) & V. Popovic (Serbia)
08:30	S12.1	The Selfish Brain: Competition for Energy Resources A. Peters (Germany)
08:50	S12.2	Peptide YY: Cure for obesity? R. Batterham (UK)
09:10	S12.3	Hypothalamic regulation of energy balance D. Cota (France)
09:30	S12.4	Metabolic and reward cues affect the central clock in the brain E.Challet (France)
08:30 - 10:00		DGE Hormone Toxicology: Is there a threat of endocrine disruptors? HALL 4/5 Chairs: A. Pfeiffer (Berlin) & G. Vollmer (Dresden)
08:30		Endocrine disruptors and the thyroid J. Kohrle (Berlin)
08:50		Endocrine disruptors and reproductive hormones H. Jarry (Göttingen)
09:10		Plant derived compunds with endocrine actions: Hops and Xanthohumols B. Hofmann (Erlangen)
09:30		Danger of combination? Interactions of low ose hormone therapy with phytoestrogens G. Vollmer (Dresden)
10:05 - 10:50		Plenary Lecture 3 HALL 1 Chairs: T. Gudermann (Germany) & R. Gaillard (Switzerland)
10:05	PL3	A cofactor network that controls PGC-1alpha activity and energy homeostasis J. Auwerx (France)
10:50 - 11:15		Coffee Break & Exhibition
11:15 - 12:45		Symposium 13 - Pro & Con: HRT or more Androgen therapy of the aging male Supported by Bayer Schering Pharma HALL 1 Chair: P. Bouchard (France)
		CON G. Forti (Italy)
		PRO B. Lunenfeld (Israel)
11:15 - 12:45		Symposium 14: Basic Highlights HALL 7 Chairs: J. Castano (Spain) & J. C. Moreno (Netherlands)
11:15	S14.1	Direct vizualization of cyclic AMP levels in three dimensional cultures of thyroid follicles D. Calebiro (Germany)
11:30	S14.2	Dopamine receptor 2 activation reduces cells viability in non functioning pituitary adenomas by inhibiting Vascular Endothelial Growth Factor secretion M. C. Zatelli (Italy)
11:45	S14.3	Variants of the phosphodiesterase 11A (PDE11A4) gene and genetic predisposition to adrenocortical tumors (ACT) R. Libé (France)
12:00	S14.4	Targeted disruption of Slc2a8 (GLUT8) reduces ATP levels and mitochondrial potential of spermatozoa V. Gawlik (Germany)
12:15	S14.5	KLF11 differentially regulates PDX1-induced activation of the human insulin promoter in rodent beta-cells and human non-beta-cells N. Perakakis (Germany)
12:30	S14.6	Specific neuronal deletion of cannabinoid type 1 receptor (CB1) mice exhibits reduced fat mass and diet-induced obesity resistance C. Cervino (Italy)
11:15 - 12:45		Symposium 15 - Clinical: GH treatment of syndromic short stature-facts and myths HALL 3 Chairs: M. Ranke (Germany) & D. Micic (Serbia)
11:15	S15.1	SHOX Deficiency: Does GH Treatment Do any Good? W. F. Blum (USA/Germany)
11:35	S15.2	GH therapy in Noonan Syndrome – facts and myths J. Dahlgren (Sweden)
11:55	S15.3	GH therapy in children with Prader Willi Syndrome (PWS) A. Hokken-Koelega (Netherlands)
12:15	S15.4	Consensus on GH Treatment in SGA P. Clayton (UK)
11:15 - 12:45		Oral Communication 3: Diabetes and Obesity HALL 4/5 Chairs: M. Coculescu (Romania) & U. Pagotto (Italy)
11:15	OC3.1	Interaction of hypothalamic G-protein-coupled receptors (GPCRs) involved in weight regulation Presenter: A. Rediger (Germany)
11:25	OC3.2	Adiponectin inhibits AMP kinase activity and increases insulin secretion in MIN6 cells Presenter: J. R. Rao (Australia)
11:35	OC3.3	Regulation of lipolysis by corticotropin releasing hormone in brown adipocytes Presenter: D. Markovic (UK)
11:45	OC3.4	Fatty acid-induced induction of TLR-4/NFkB-pathway in adipocytes links nutritional signaling with innate immunity Presenter: A. Schäffler (Germany)
11:55	OC3.5	Hormonal regulation of 11-β-HSD1 expression and activity in differentiated 3T3- L1 adipocytes Presenter: A. M. Isidori (Italy)
12:05	OC3.6	Transcriptional control of hepatic and systemic lipid metabolism by the nuclear receptor co-factor RIP140 Presenter: M. Berriel Diaz (Germany)
12:15	OC3.7	Impact of metformin on gene expression, glucose uptake and lipolysis in adipocytes Presenter: D. Hadaschik (UK)
12:25	OC3.8	Retrovirally transduced, antigen-specific T cells for therapy of type 1 diabetes Presenter: E. Jaeckel (Germany)
12:35	OC3.9	Effect of baseline sample characteristics, comparator drug, co-interventions and rosigitazone doses on the risk of myocardial infarction. Multivariable lineal regression analysis Presenter: J. Sapunar (Chile)
13:00 - 14:30		Satellite Symposium: Pfizer - The role of pegvisomant in the current treatment of acromegaly HALL 1
13:00 - 14:30		Lunch
13:00 - 15:30		STAND BY ME!! SESSION All poster authors will discuss posters during lunch. Members of the Executive & Program Committees will be active participants. EXHIBITION & UPPER FLOOR
14:30 - 15:30		Meet the Expert 5: How valid is a biochemical diagnosis of chromaffin tumors? HALL 1
14:30	ME5	How valid is a biochemical diagnosis of chromaffin tumors? F. Mantero (Italy)
14:30 - 15:30		Meet the Expert 6: Beyond the bone – sporadic and hereditary hyperparathyroidism. HALL 7
14:30	ME6	Beyond the bone – sporadic and hereditary hyperparathyroidism. M. Toth (Hungary)
14:30 - 15:30		Meet the Expert 7: The sequelae of brain injury – is the pituitary involved? HALL 3
14:30	ME7	The sequelae of brain injury – is the pituitary involved? F. Tanriverdi (Turkey)
14:30 - 15:30		Meet the Expert 8: MicroRNA HALL 4/5
14:30	ME8	microRNA M. Scherr (Germany)
15:30 - 17:00		Symposium 16 - Clinical: New insights in PCOS HALL 1 Chairs: A. Milewicz (Poland) & S. Christin-Maitre (France)
15:30	S16.1	Definition of PCOS B. Fauser (Netherlands)
15:50	S16.2	New insights in Polycystic Ovary Syndrome L. Ibáñez (Spain)
16:10	S16.3	Vascular markers in PCOS E. Diamanti-Kandarakis (Greece)
16:30	S16.4	Treatment of PCOS B. Bidzinska-Speichert (Poland)
15:30 - 17:00		Symposium 17 - Basic: Thyroid Cell Biology HALL 7 Chairs: J. Köhrle (Germany) & T.Visser (Netherlands)
15:30	S17.1	Basic mechanisms of thyroid development S. Zannini (Italy)
15:50	S17.2	Growth Factors Involved In Thyroid Cells Differentiation P. Santisteban (Spain)
16:10	S17.3	Molecular mechanisms of thyroid carcinogenesis: role of the CBX7 gene.Loss of the CBX7 gene.ll A. Fusco (Italy)
16:30	S17.4	Novel insights on the Na+/I- symporter (NIS): it mediates electroneutral active transport of the environmental pollutant perchlorate. N. Carrasco (USA)
15:30 - 17:00		Oral Communication 4: Bone & Adrenal HALL 4/5 Chairs: D. Schnabel (Germany) & A. Leal-Cerro (Spain)
15:30	OC4.1	Inactivation of the Carney Complex (CNC) gene 1 (PKA regulatory subunit 1A, PRKAR1A) by interference RNA alters multiple signaling pathways and decreases apoptosis. Presenter: B. Ragazzon (France)
15:40	OC4.2	Reduced fertility rates and high prevalence of testicular adrenal rest tumors (TART) in male patients with congenital adrenal hyperplasia Presenter: N. Reisch (Germany)
15:50	OC4.3	BMP dependent modulation of adrenocortical growth and function Presenter: I. K. Johnsen (Germany)
16:00	OC4.4	Comparison of different test systems for the screening of inhibitors of CYP11B enzymes Presenter: A. Stuermer (Germany)
16:10	OC4.5	Comparison of 1-mg versus 8-mg dexamethasone suppression tests (DST) in patients with clinically inapparent adrenal adenoma. Presenter: G. Reimondo (Italy)
16:20	OC4.6	Isolation and characterization of cells coexpressing endothelial progenitors and parathyroid specific genes from human adult normal and tumoral parathyroids Presenter: S. Corbetta (Italy)
16:30	OC4.7	Molecular analysis of the calcium sensing receptor (CASR) gene in 40 patients clinically suspected to have familial hypocalciuric hypercalcemia (FHH) Presenter: F. Defrance-Faivre (France)
16:40	OC4.8	Incidental parathyroidectomy during thyroid surgery: outcome, follow-up and management of 231 patients treated between 1989 and 2007 Presenter: B. Feldmann (Germany)
16:50	OC4.9	Teriparatide (TPTD) Treatment Followed by Either Zoledronic Acid (ZOL) 5mg Once Yearly or Strontium Ranelate (SR) 2g Daily: Preliminary Results from the ZOSTER-Study Presenter: G. Riedmüller (Austria)
15:30 - 17:00		DGE Symposium Young Reasearchers (DGE): Embryonic Development of Endocrine Organs Sponsored by Merck Serono HALL 3 Chairs: B. Allolio (Würzburg) & O. Hiort (Lübeck)
15:30		Trekking the midline-development of the hypothalamus and the pituitary Dr. Pogoda (Freiburg)
15:50		Sexual differentiation - What makes the difference? P. -M. Holterhus (Kiel)
16:10